Chasing a mammoth target of 222 in New Delhi on Wednesday, Bangladesh stumbled in their chase as the Indian spinners took wickets at regular intervals, with all seven bowlers claiming at least one wicket and Hardik Pandya taking three catches.
Mahmadullah, 38, was the only Bangladesh batter to hold up India with a knock of 41, but he had little support as wickets tumbled around him.
Bangladesh, who won the toss, started strongly and their pace attack removed India's top-order inside the powerplay.
The hosts were reeling at 3-41 after openers Sanju Samson and Abhishek Sharma, and skipper Suryakumar Yadav were sent back cheaply.
Reddy and Rinku then took charge, sharing a 108-run stand off 49 balls, rotating the strike effectively and going after the spinners.
Reddy was India's top-scorer with 74 off 34 balls, including four fours and seven sixes, and they plundered 26 runs off one over from Mehidy Hasan Miraz.
Rinku also notched a half-century (53) and Pandya added 32 off 19 as India posted a total of 9-221.
Taskin Ahmed was the pick of the Bangladesh bowlers with figures of 2-16 and Rishad Hossain (3-55) claimed three wickets in the final over.
Hyderabad will host the last match of the series on Saturday.Â
