Both were killed in vehicle accidents.
The state’s highest number of deaths per local government area was in Wellington Shire in Gippsland, with four deaths.
Greater Shepparton recorded three deaths — the equal second most in regional Victoria.
In total, 61 people lost their lives across Victoria in workplace accidents last year.
There were 173 injury claims made in Campaspe across the reporting period.
WorkSafe chief executive officer Colin Radford is urging Victorians to think about safety in their own workplaces while reflecting on the lasting impact of deaths and serious injuries.
“Both employers and workers should understand that there is no such thing as unavoidable workplace harm,” he said.
“Every single work-related death and injury in 2022 could have been prevented, along with the pain and suffering endured by the families, friends and colleagues of those impacted.”
Mr Radford said WorkSafe would continue to target high-risk industries and sectors to ensure the right measures were in place to control their specific health and safety risks.
“It’s incredibly frustrating that we are still seeing the same type of incidents happen in workplaces where the hazards and controls should be well known,” he said.
“WorkSafe has a range of enforcement tools at its disposal for duty holders who fail to provide a safe and healthy workplace, including possible court action with significant potential penalties.”